CMaT will enable robust, scalable, low-cost biomanufacturing of high-quality therapeutic cells to bring affordable, curative therapies against incurable chronic diseases to everyone. This will transform healthcare, improve the economy, add new jobs, and enhance national security.

http://cellmanufacturingusa.org/

The Center for 3D Medical Fabrication (3DMedFab) at Georgia Tech provides rapid prototyping of a wide range of multiple biomaterials in 3D.

http://3dmedfab.gatech.edu/

How life began is arguably the most intriguing question of our time. Determining the chemistry required for the de novo appearance of life is also an important scientific problem, as its solution will have a major impact on chemistry, other scientific fields and the general public. The long-term research objective of our CCI is to demonstrate that small molecules within a model inventory of prebiotic chemistry can self-assemble into polymers that resemble RNA and proteins. The members of this Center hold the common belief that achieving a “one pot” self-assembly of life-like polymers is a realistic goal.

http://www.centerforchemicalevolution.com

The Center for Drug Design Development & Delivery, or CD4, is an incomparable center that seeks to provide new and refreshing ideas and interpretations to traditional pharmaceutical research. CD4 is making grand strides in accomplishing these efforts by operating through its three main projects: the Pharmaceutical Pipeline Project, the Vaccine Technology Project, and the Pharmaceutical Education Project.

http://cd4.gatech.edu

At the Center for Immunoengineering at Georgia Tech engineers, chemists, physicists, computational scientists, and immunologists come together to collaboratively understand how the immune system works and find breakthrough solutions to improve the lives of patients suffering from cancer, infectious diseases (e.g. HIV, tuberculosis, hepatitis, polio etc.), autoimmune and inflammatory disorders (e.g. diabetes, lupus, multiple sclerosis, arthritis, fibrosis, asthma etc.) as well as those undergoing regenerative therapies (e.g. organ transplantation, spinal cord injury, bone and cartilage repair, etc.).

https://immunoengineering.gatech.edu/

The Center for Integrative Genomics (CIG) at Georgia Tech is a virtual affiliation of researchers interested in the application of genome-wide research strategies to diverse biological themes. The goals of the center are to: Conduct quantitative genetic analysis of Genomes, Transcriptomes, Proteomes, Metabolomes and Phenomes and foster partnerships within the School of Biology, across Georgia Tech, and with collaborators in the Atlanta region.

https://cig.gatech.edu/

The Center utilizes the combined expertise of Georgia Tech and Emory University researchers who employ a variety of in vivo, in vitro and in silico approaches and represent different fields of study, including: genetics; molecular, cellular and structural biology; chemistry, biochemistry and synthetic biology; chemical, biomolecular and biomedical engineering; bioinformatics and computational biology. NanoMAD's mission is to develop new technologies for detecting, monitoring and controlling self-assembled macromolecular complexes at various levels, including their pathogenic consequences, biological roles and evolutionary origin.

http://www.nanomad.gatech.edu

The Cool Center is a part of NASA’s Prebiotic Chemistry and Early Earth Environments (PCE3) Consortium, one of five Research Coordination Networks within the Astrobiology Program. The PCE3 Consortium is focused on investigating the delivery and synthesis of small molecules under the conditions of the Early Earth, and the subsequent formation of proto-biological molecules and pathways that lead to systems harboring the potential for life.

https://cool.gatech.edu/

The Center for Pharmaceutical Development (CPD), established in February 2010, provides a forum for academic and industrial scientists to develop novel approaches for the improvement of pharmaceutical API manufacturing, for product formulation, and for analytical methods. The distinctive strengths of each of the University partners will provide industrial participants with unique opportunities to advance topics on the manufacturing, formulation and analysis of pharmaceuticals. The Center facilitates technologies such as the creation of more selective and robust biological and chemical catalysts that allow more streamlined processes, the development of improved methods for stabilizing drugs and vaccines to protect the nation’s drug supply, and the design of new techniques for the nondestructive evaluation of pharmaceutical products.

http://cpd.gatech.edu

The Center's research program has three components of increasing complexity, plus an enabling technologies thrust. EBICS' educational programs aim at producing the next generation of research and education leaders who are truly knowledgeable in both biology and engineering, and who will potentially shape how research and education are done in this new field. The Center will also engage faculty from minority-serving institutions on research projects, and work closely with existing outreach and recruitment programs at all partner institutions to ensure the broadest range of participation in all of its programs.

http://ebics.net

The Georgia Center for Medical Robotics (GCMR) brings together people with expertise in several areas of medicine as well as technology development from the nano-scale to macro-scale. GCMR is highly interdisciplinary, comprised of people from the Georgia Institute of Technology, Emory University, Children’s Healthcare of Atlanta (CHOA), and Morehouse School of Medicine. One of its unique features is that it addresses the needs of both adult and pediatric populations.

http://medicalrobotics.gatech.edu

Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M) is the first such research center in the United States. The current state-of-the-art in cell therapies involves small scale, hospital-centric processing of cells, operated with minimal characterization, and little involvement of process engineering and QA/QC concepts leading to wide variability and uncertainty in clinical trials. In addition to developing new tools and technologies, standards development will be a long term goal of Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M).

https://cellmanufacturing.gatech.edu/

The Nanomedicine Center for Nucleoprotein Machines focuses on understanding and re-directing natural processes for repair of damaged DNA. Human cells have many different repair pathways, each of which involves a different type of nucleoprotein machine. The Center’s five-year goal is to re-engineer the homologous recombination repair machine to provide a clinically applicable gene correction technology. The Center’s vision is to design, produce, deliver, and validate a gene correction device based on engineered zinc finger nucleases. The device will home to the defective gene in the patient’s hematopoietic stem cells and make a precise cut to activate the HR machine, which will replace the mutation with the correct beta-globin sequence. The approach can potentially be extended for treatment of other single-gene disorders.

http://www.nucleoproteinmachines.org

The Neural Engineering Center develops cutting-edge science and technology for measuring, understanding, modifying, and stimulating neural activity. There is a critical need for novel collaborative integration between researchers developing interfacing technologies and those advancing our scientific understanding of brain and nervous system function. Applications of these technologies span advancing understanding of neural function to translational methods that improve clinical outcomes.

https://neuro.gatech.edu/

The Pediatric Technology Center (PTC) brings clinical experts together with Georgia Tech scientists and engineers to develop technological solutions to problems in the health and care of children. The PTC provides extraordinary opportunities for interdisciplinary collaboration in pediatrics, creating breakthrough discoveries that often can only be found at the intersection of multiple disciplines. These collaborations also allow us to bring discoveries to the clinic and the bedside, thereby enhancing the lives of children and young adults.

https://ptc.gatech.edu/

The Regenerative Engineering and Medicine (REM) research center is a joint collaboration between Emory University and Georgia Tech. REM is specifically focused on endogenous repair or how the body can harness its own potential to heal or regenerate. Bone, muscle, nerves, heart, blood vessels, and other tissues each have a baseline ability to regenerate. REM investigators ask what can be done when trauma or disease in humans overwhelms the ability of tissues or organs to regenerate on their own.

http://regenerativeengineeringandmedicine.com